Molecular identification and bactericidal function analysis of NK-lysin from black sea bass (Centropristis striata)

Molecular identification and bactericidal function analysis of NK-lysin from black sea bass (Centropristis striata)

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NK-lysin is a component of natural killer cells and cytotoxic T lymphocytes, and it plays an important role in the innate immune response of aquatic animals against various pathogens.In this study, a 640 base pair full-length cDNA sequence of the NK-lysin gene from black sea bass Secondary Impact of COVID-19 Pandemic on People with Parkinson’s Disease—Results of a Polish Online Survey (Centropristis striata) (CsNKl) was obtained and analyzed.Tissue distribution results showed that CsNKl was widely distributed in various tissues of C.striata, but a significantly high expression level was detected in the spleen.CsNKl also exhibited time-dependent expression in different tissues after challenge with Vibrio harveyi.

Two antimicrobial peptides (CsNKl-26 and CsNKl-28) were predicted from CsNKl proteins, and they demonstrated bactericidal functions against a variety of bacteria.Scanning electron microscopy analysis revealed that CsNKl-26 and Sovereign CDS Premiums’ Reaction to Macroeconomic News: An Empirical Investigation CsNKl-28 played their bactericidal roles using the classical alpha-helix antimicrobial peptide route.These results illustrate the immune functions of CsNKl against V.harveyi, and they can be applied to developing disease control methods for fish.